Receptor tyrosine kinase profiling

Details Receptor tyrosine kinase profiling Receptor tyrosine kinase profiling

G - Physics

01

N

G01N 33/574 (2006.01)

Patent

CA 2683804

The invention provides novel methods for designing and administering therapeutic treatments for subjects afflicted with cancer. One aspect provides methods of identifying activated RTK pathways in a cancer and formulating treatment plans based on a plurality of RTK inhibitors. The invention further provides methods for evaluating candidate tyrosine kinase inhibitors for therapeutic efficacy.

L'invention concerne de nouveaux procédés pour concevoir et administrer des traitements thérapeutiques pour des sujets atteints de cancer. Un aspect concerne des procédés pour identifier des voies des RTK activées dans un cancer et formuler des plans de traitement à partir d'une pluralité d'inhibiteurs des RTK. L'invention concerne en outre des procédés pour évaluer des inhibiteurs des tyrosine kinases candidats présentant une efficacité thérapeutique.

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