Methods and compositions for isolation and growth of kidney...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/08 (2006.01) A61F 2/02 (2006.01) A61K 35/23 (2006.01) A61K 38/18 (2006.01) C12M 3/06 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2131305

2131305 9317696 PCTABS00025 Methods, including culture media conditions, which provide for isolation and purification of renal tubule stem cells and for in vitro) kidney tubulogenesis are disclosed. The methods rely on culturing adult kidney cells in a culture media treated with combinations of transforming growth factor-.beta.1, epidermal growth factor, and all-trans retinoic acid.

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