Methods and means of detecting nitric oxide synthase

Details Methods and means of detecting nitric oxide synthase Methods and means of detecting nitric oxide synthase

C - Chemistry, Metallurgy

12

Q

C12Q 1/26 (2006.01) C12M 1/34 (2006.01) C12M 1/40 (2006.01) C12Q 1/527 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2248558

Methods for identifying and monitoring increased or decreased levels of inducible nitric oxide synthase in biological samples are provided. A collection device for detecting inducible nitric oxide synthase in biological samples is also provided. Detection of inducible nitric oxide synthase is useful in the diagnosis of inflammatory responses such as infections mediated by bacteria, yeast or viruses, transplant rejection, rheumatoid arthritis, interstitial cystitis and cancer.

L'invention concerne des procédés d'identification et de contrôle d'augmentation ou de diminution de niveaux d'une synthase d'oxyde nitrique inductible dans des échantillons biologiques. Un dispositif collecteur pour la détection d'une synthase d'oxyde nitrique inductible dans des échantillons biologiques est également décrit. La détection d'une synthase d'oxyde nitrique inductible est utile pour diagnostiquer des réponses inflammatoires telles que des infections induites par des bactéries, des levures ou des virus, un rejet de greffe, le rhumatisme articulaire, la cystite interstitielle et le cancer.

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