Compounds for blocking androgen receptors

Details Compounds for blocking androgen receptors Compounds for blocking androgen receptors

C - Chemistry, Metallurgy

07

C

C07C 49/543 (2006.01) A61K 31/12 (2006.01) C07C 45/59 (2006.01) C07C 49/713 (2006.01) C07C 49/753 (2006.01)

Patent

CA 2473908

Compounds used to block non-essential androgen receptors are described. In particular, cyclohexenone compounds containing an alkyl group may be used in the treatment of conditions mediated by the blocking of non-essential androgen receptors such as acne, male patterned baldness, keloids, skin-wrinkling, and osteoarthritis. The cyclohexenone compound may be administered orally, topically, or internally.

L'invention concerne des composés utilisés pour bloquer des récepteurs androgènes non essentiels. En particulier, des composés de cyclohexénone contenant un groupe alkyle peuvent être utilisée dans le traitement d'états pathologiques ayant pour origine le blocage de récepteurs androgènes non essentiels tels que l'acné, la calvitie caractéristique chez les hommes, les chéloïdes, le plissement de la peau, et l'ostéoarthrose. Le composé de cyclohexénone peut être administré par voie buccale, topique ou interne.

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