Iodinated aromatic propanedioates

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 233/54 (2006.01) A61K 49/04 (2006.01) C07C 69/76 (2006.01) C07C 235/06 (2006.01) C07C 237/46 (2006.01) C07C 255/23 (2006.01) C07C 309/17 (2006.01) C07C 311/24 (2006.01)

Patent

CA 2119968

IODINATED AROMATIC PROPANEDIOATES ABSTRACT Compounds having the structure Image wherein (Z?COO is the residue of an iodinated aromatic acid; R1 and R2 are independently alkyl, fluoroalkyl, cycloalkyl, aryl or aralkyl; and R3 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, cyano, sulfonate, carboxamido, sulfonamido, CO2 - alkyl, CO2 -aryl or CO2 - aralkyl; are useful as contrast agents in x-ray imaging compositions and methods.

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