Multilayer collagen matrix for tissue reconstruction

Details Multilayer collagen matrix for tissue reconstruction Multilayer collagen matrix for tissue reconstruction

A - Human Necessities

61

L

A61L 27/24 (2006.01) A61L 15/32 (2006.01) A61L 27/44 (2006.01) A61L 27/50 (2006.01)

Patent

CA 2400398

A multilayer material with improved mechanical, physical, functional and handling properties for use in human and veterinary medicine in both in vivo and in vitro condition and/or for in ex vivo and/or in vivo reconstruction of tissue or organs according to the invention comprises at least one layer of a natural polymer, preferentially collagen of animal or/and human or/and recombinant or/and transgenic origin, and optionally one or more layers comprising a biocompatible synthetic polymer which may be or not biodegradable, and is obtainable by subjecting the combined layers to a defined heat and defined pressure treatment. The materials of the layers may optionally also contain biologically active substances or substances which improve mechanical, functional, biological and/or handling properties of the material.

La présente invention concerne une matière multicouches dotée de propriétés mécaniques, physiques, fonctionnelles et de manipulation améliorées, qui est utilisée en médecine humaine et vétérinaire tant in vivo que in vitro et/ou pour la reconstruction ex vivo et/ou in vivo de tissus ou d'organes, qui comprend au moins une couche d'un polymère naturel, de préférence un collagène d'origine animale et/ou humaine et/ou recombinée et/ou transgénique, et, facultativement, une ou plusieurs couches comprenant un polymère synthétique biocompatible qui peut être biodégradable ou non, et que l'on peut obtenir en soumettant les couches combinées à un traitement sous une chaleur et une pression définies. Les matières qui composent les couches peuvent aussi contenir facultativement des substances biologiquement actives ou des substances qui améliorent les propriétés mécaniques, fonctionnelles, biologiques et/ou de manipulation de la matière de l'invention.

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