Compositions and methods for treatment of autoimmune and...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/35 (2006.01) A61K 39/39 (2006.01) A61P 19/02 (2006.01) A61P 37/08 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2708942

The present invention provides improved methods and compositions for treating and preventing autoimmune and allergic diseases. More specifically the invention relates to new immuno- modulating complexes which are fusion proteins comprising mutant subunits of bacterial endotoxins, a peptide capable of binding to a specific cellular receptor, and one or more epitopes associated with an autoimmune or allergic disease.

La présente invention porte sur de meilleurs procédés et sur de meilleures compositions pour le traitement et la prévention de maladies auto-immunes et allergiques. De façon plus précise, l'invention porte sur de nouveaux complexes immuno-modulants qui sont des protéines de fusion comprenant des sous-unités mutantes d'endotoxines bactériennes, un peptide qui peut se lier à un récepteur cellulaire spécifique, et un ou plusieurs épitopes associés à une maladie auto-immune ou allergique.

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