Glycated milk and uses thereof

A - Human Necessities – 23 – C

Patent

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Details

A23C 9/152 (2006.01) A23L 1/305 (2006.01) A61K 38/08 (2006.01)

Patent

CA 2685005

A "sleep milk" including peptides having a soporific effect on humans or other mammals uses milk proteins from cows homozygous for the A1 allele for beta-casein. Exposing the milk or the proteins to a glycation-enhancing process substantially increases the half-life of the resulting peptides like beta-casomorphin-7 after ingestion, hydrolysis in the gut and absorbtion- through the gut wall. The sleep milk is made by glycating A1 milk within a modified UHT process in the presence of carbohydrates like ascorbic acid. The soporific effect of the resulting product is estimated by measurement of the glycation products.

Un <= Lait favorisant le sommeil >=, comprenant des peptides ayantun effet soporifique sur les hommes ou d'autres mammifères, utilise des protéines de lait provenant de vaches homozygotes au niveau de l'allèle A1 pour la bêta-caséine. L'exposition du lait ou des protéines à un processus de promotion de la glycation augmente sensiblement la demi-vie des peptides résultants comme la bêta-casomorphine-7 après l'ingestion, l'hydrolyse dans l'intestin et l'absorption à travers la paroi de l'intestin. Le lait favorisant le sommeil est fabriqué en glyquant du lait A1 au cours d'un processus UHT modifié en présence de glucides tels que de l'acide ascorbique. L'effet soporifique du produit résultant est estimé par la mesure des produits de glycation.

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