Preventive and/or therapeutic agents for diabetic vascular...

Details Preventive and/or therapeutic agents for diabetic vascular... Preventive and/or therapeutic agents for diabetic vascular...

A - Human Necessities

61

K

A61K 31/122 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2609595

A preventive and/or therapeutic agent for either or both of a diabetic vascular disorder or/and a diabetic respiratory disorder, comprising a cyclohexenone long-chain alcohol represented by the following general formula (1) as an active ingredient: (1) (wherein each of R1, R2 and R3 represents a hydrogen atom or a methyl group and X represents a linear or branched alkylene or alkenylene group having 10 to 28 carbon atoms) are/is provided. Because the cyclohexenone long-chain alcohol represented by the general formula (1) improves diabetic vascular smooth muscle contraction and bronchial smooth muscle contraction, it is useful as a preventive and/or therapeutic agent for a diabetic vascular disorder and respiratory disorder.

L~invention concerne un agent préventif et/ou thérapeutique pour un trouble vasculaire diabétique ou/et un trouble respiratoire diabétique, comprenant un alcool cyclohexénone à longue chaîne représenté par la formule générale (1) suivante comme ingrédient actif : (1) (où chacun de R1, R2 et R3 représente un atome d~hydrogène ou un groupe méthyle et X représente un groupe alkylène ou alcénylène linéaire ou ramifié ayant de 10 à 28 atomes de carbone). Du fait que l~alcool cyclohexénone à longue chaîne représenté par la formule générale (1) améliore la contraction du muscle lisse vasculaire et la contraction du muscle lisse bronchique diabétiques, il est utile comme agent préventif et/ou thérapeutique pour un trouble vasculaire et un trouble respiratoire diabétiques.

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