Pharmaceutical composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/70 (2006.01) A01N 59/00 (2006.01) A61K 31/00 (2006.01) A61K 31/351 (2006.01) A61K 31/44 (2006.01) A61K 31/56 (2006.01) A61K 31/706 (2006.01) A61K 31/7064 (2006.01) A61K 31/7068 (2006.01) A61K 31/7076 (2006.01) A61K 31/708 (2006.01) A61K 38/00 (2006.01) A61P 1/00 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 3/10 (2006.01) A61P 7/04 (2006.01) A61P 7/06 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 13/10 (2006.01) A61P 13/12 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P

Patent

CA 2327431

The invention relates to the use of a compound of formula (I), wherein R1 is a base defined by one of the formulae (a), (b), (c) and (d), and R2 is hydrogen, C1-C4 alkyl, bromine, fluorine, chlorine or iodine, or a pharmaceutically acceptable salt thereof, for producing a medicament for immunosuppressive therapy of the human or animal body. The invention also relates to combination preparations with cyclosporine A, tacrolismus, mycophenolatemofetil, daclizumab, rapamycin and/or one or more corticosteroids.

L'invention concerne l'utilisation d'un composé de la formule (I) où R¿1? représente une base définie par une des formules (II), (III), (IV), (V), et R¿2? représente de l'hydrogène, alkyle C¿1?-C¿4?, du brome, du fluor, du chlore ou de l'iode, ou bien un sel pharmaceutiquement acceptable de ce composé en vue de préparer un médicament destiné à un traitement immuno-suppresseur de l'organisme humain ou animal.

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