C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)
Patent
CA 2386365
The invention provides a method for determining the presence of leptin, based on detecting leptin-induced angiopoietin-2 expression in some cells or cell lines, e.g. murine Swiss 3T3 F442A preadipocytes or human marrow stromal cell line hMS2-12. Leptin detection is e.g. performed transfecting cells with a vector comprising a reporter gene (e.g. Green Fluorescent Protein (GFP)) under the control of angiopoietin-2 promoter.
La présente invention concerne une méthode permettant de déterminer la présence de leptine dans un échantillon.
Cohen Batya
Rubinstein Menachem
Borden Ladner Gervais Llp
Yeda Research And Development Co. Ltd.
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