Methods of using and compositions comprising...

A - Human Necessities – 61 – K

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Details

A61K 31/454 (2006.01) A61K 31/496 (2006.01) A61K 31/724 (2006.01)

Patent

CA 2477301

Methods of treating, preventing and/or managing myelodysplastic syndromes are disclosed. Specific methods encompass the administration of immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active ingredient, and/or the transplantation of blood or cells. Specific second active ingredients are capable of affecting or blood cell production. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.

La présente invention se rapporte à des méthodes permettant de traiter, prévenir et/ou gérer les syndromes myélodysplastiques. Des méthodes spécifiques incluent l'administration d'un composé immunomodulateur, ou d'un sel, solvate, hydrate, stéréoisomère, clathrate ou promédicament pharmaceutiquement acceptable de ce composé, utilisé seul ou en combinaison avec un second ingrédient actif, et/ou la transplantation de cellules sanguines. De seconds ingrédients actifs spécifiques peuvent affecter la production de cellules sanguines. L'invention se rapporte également à des compositions pharmaceutiques, des formes posologiques monodoses et à des trousses pouvant être utilisées dans les procédés décrits ci-dessus.

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