Spiro tetracyclic compound

Details Spiro tetracyclic compound Spiro tetracyclic compound

C - Chemistry, Metallurgy

07

D

C07D 471/22 (2006.01) A61K 31/499 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2651420

Disclosed is an anti-coagulant which has extremely excellent inhibitory effect on FXa and an extremely poor inhibitory effect on hERG channel, and can be administered through the oral route. Specifically, disclosed is a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof.

L'invention concerne un anticoagulant ayant un effet inhibiteur de FXa particulièrement excellent et un effet inhibiteur du canal hERG particulièrement faible, ledit anticoagulant pouvant être administré par voie orale. L'invention concerne plus spécifiquement un composé répondant à la formule (I) ou l'un de ses sels acceptable sur le plan pharmaceutique.

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