Assay for detection of translocase enzyme activity in drug...

Details Assay for detection of translocase enzyme activity in drug... Assay for detection of translocase enzyme activity in drug...

C - Chemistry, Metallurgy

12

Q

C12Q 1/48 (2006.01) C12Q 1/18 (2006.01) G01N 33/53 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2407718

The invention provides a method for assaying the activity of the translocase enzyme involved in peptidoglycan biosynthesis in bacteria using scintillation proximity assay methodology. The method is suitable for high throughput screening of potential anti-bacterial drugs.

L'invention concerne un procédé permettant de tester l'activité de l'enzyme translocase impliquée dans la biosynthèse de peptidoglycane de bactéries par un processus de dosage de la scintillation par proximité. Ce procédé convient à un tri à haut rendement de drogues antibactériennes potentielles.

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