Synthetic peptides which reduce or eliminate bags formed...

Details Synthetic peptides which reduce or eliminate bags formed... Synthetic peptides which reduce or eliminate bags formed...

C - Chemistry, Metallurgy

07

K

C07K 5/103 (2006.01) A61K 38/07 (2006.01) A61P 7/10 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2583670

The invention relates to peptides having general formula (I), which can reduce or eliminate bags formed under the eyes, the stereoisomers thereof and racemic or non-racemic mixtures of same and the cosmetically- or dermopharmaceutically- acceptable salts thereof, wherein: X is cysteinyl, seryl, threonyl or aminobutyryl; R1 is H or an alkyl, aryl, aralkyl or acyl group; and R2 is amino, hydroxyl or thiol, all of which may or may not be substituted with aliphatic or cyclic groups. The invention also relates to a method of obtaining said peptides, to cosmetic or dermopharmaceutical compositions containing same and to the use thereof for treating the skin, preferably in order to reduce or eliminate bags formed under the eyes.

L'invention concerne des peptides représentés par la formule générale (I), capables de réduire ou d'éliminer les poches sous les yeux. L'invention concerne également des stéréoisomères et des mélanges de peptides, racémiques ou non, ainsi que leurs sels de qualité cosmétique ou dermopharmaceutique. Dans la formule générale (I), X désigne un résidu cystéinyle, séryle, thréonyle ou aminobutyryle ; R1 désigne un atome H ou un groupe alkyle, aryle, aralkyle ou acyle ; et R2 désigne un groupe amino, hydroxyle ou thiol, chacun substitué ou non par des groupes aliphatiques ou cycliques. L'invention concerne également un procédé d'obtention de ces peptides, des compositions cosmétiques ou dermopharmaceutiques contenant ces peptides, et leur utilisation pour traiter la peau, de préférence pour réduire ou éliminer les poches sous les yeux.

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