Methods and compositions for identifying therapeutic compounds

Details Methods and compositions for identifying therapeutic compounds Methods and compositions for identifying therapeutic compounds

C - Chemistry, Metallurgy

12

Q

C12Q 1/44 (2006.01)

Patent

CA 2543144

By the present invention, enzymes responsible for prodrug activation are identified and utilized for the identification of candidate compounds as prodrugs. The present invention includes methods for identifying a candidate compound as a suitable prodrug as well as methods of screening candidate compounds for suitability as therapeutic agents.

L'invention concerne l'identification d'enzymes responsables de l'activation de promédicaments et l'utilisation de celles-ci pour l'identification de composés candidats à utiliser comme promédicaments. L'invention concerne également des procédés d'identification d'un composé candidat à utiliser comme promédicament approprié, ainsi que des procédés de balayage de composés candidats permettant de déterminer si ceux-ci sont appropriés pour être utilisés comme agents thérapeutiques.

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