Anti-tnf antibodies and methotrexate in the treatment of...

Details Anti-tnf antibodies and methotrexate in the treatment of... Anti-tnf antibodies and methotrexate in the treatment of...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/505 (2006.01) C07K 16/24 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2261630

Methods for treating and/or preventing a TNF-mediated disease in an individual are disclosed. Also disclosed is a composition comprising methotrexate and an anti-tumor necrosis factor antibody. TNF-mediated diseases include rheumatoid arthritis, Crohn's disease, and acute and chronic immune diseases associated with transplantation.

Procédés de traitement et/ou de prévention des maladies induites par le facteur de nécrose tumorale (TNF) chez un individu. L'invention décrit également une composition comprenant du méthotrexate et un anticorps anti-TNF. Les maladies induites par le facteur TNF comprennent la polyarthrite rhumatoïde, la maladie de Crohn ainsi que les maladies immunitaires aiguës et chroniques liées aux transplantations.

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