C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 7/08 (2006.01) A61K 31/42 (2006.01) A61K 31/4439 (2006.01) A61K 31/501 (2006.01) A61K 31/695 (2006.01) A61P 1/00 (2006.01) A61P 25/22 (2006.01) A61P 29/00 (2006.01) C07D 257/04 (2006.01) C07D 261/06 (2006.01) C07D 401/04 (2006.01) C07D 403/14 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2665083
The present invention is directed to compounds of formula (I) Wherein R1 to R5, X and Z are further defined in the description. The invention also relates to processes for the preparation of the compounds and to intermediates used in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
La présente invention concerne des composés de formule (I) dans laquelle R1 à R5, X et Z sont définis de façon plus détaillée dans la description. L'invention porte également sur des procédés de préparation des composés et sur des intermédiaires utilisés dans la préparation, sur des compositions pharmaceutiques contenant les composés et sur l'utilisation des composés en thérapie.
Dove Peter
Edwards Louise
Isaac Methvin
Slassi Abdelmalik
Stefanac Tomislav
Astrazeneca Ab
Fetherstonhaugh & Co.
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