A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 19/02 (2006.01)
Patent
CA 2746827
The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA). In accordance with the present invention, an antagonist of GM-CSF can be effective in the treatment of osteoarthritis. An antagonist of GM-CSF includes, but is not limited to, an antibody that is specific for GM- CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.
L'invention porte d'une manière générale sur une méthode de traitement et/ou de prophylaxie de l'arthrose. Selon l'invention, un antagoniste du GM-CSF peut être efficace pour le traitement de l'arthrose. Un antagoniste du GM-CSF comprend non exclusivement un anticorps spécifique du GM-CSF ou du récepteur du GM-CSF. L'invention porte en outre sur des animaux transgéniques tels que la souris knock-out GM-CSF s'avérant utile pour tester des antagonistes dans certains modèles de maladies.
Cook Andrew David
Hamilton John Allan
Borden Ladner Gervais Llp
The University Of Melbourne
LandOfFree
Osteoarthritis treatment does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Osteoarthritis treatment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Osteoarthritis treatment will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1718047