N-linked aryl heteroaryl inhibitors of lta4h for treating...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/56 (2006.01) A61K 31/4035 (2006.01) A61K 31/416 (2006.01) A61P 29/00 (2006.01) C07D 209/44 (2006.01) C07D 209/48 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2634699

The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula: They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

La présente invention concerne un genre chimique d'hétérocyles biaryle à liaison azote, inhibiteurs de la LTA4H (leucotriène A4 hydrolase). Le composés sont représentés par la formule suivante, et sont utilisés dans le traitement et la prévention de la prophylaxie de maladies et de troubles inflammatoires.

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