Anti-retroviral functionalised aromatic compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 207/44 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 207/448 (2006.01) C07D 401/10 (2006.01)

Patent

CA 2321219

The invention concerns the use of an organic compound comprising an aromatic cycle substituted by at least a hydrocarbon substituent containing at least one proton donor or acceptor function capable of one or several hydrogen bonds to bring about the allosteric inhibition of the Tat protein.

La présente invention a pour objet l'utilisation d'un composé organique comprenant un cycle aromatique substitué par au moins un substituant hydrocarboné comportant au moins une fonction donneur ou accepteur de proton susceptible d'engager une ou des liaisons hydrogène, pour provoquer l'inhibition allostérique de la protéine Tat.

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