Chimeric proteins which block complement activation

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61P 37/00 (2006.01) C07K 1/16 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12N 15/62 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2172610

The present invention relates to novel chimeric proteins comprising a first polypeptide which inbibits complement activation, linked to a second polypeptide which inhibits complement activation, nucleic acids encoding novel chimeric proteins and methods of reducing inflammation with the administration of the chimeric proteins of the invention.

La présente invention concerne de nouvelles protéines chimériques comprenant un premier polypeptide qui inhibe l'activation de complément, ce premier polypeptide étant lié à un second polypeptide qui inhibe l'activation de complément, des acides nucléiques codant les nouvelles protéines chimériques, ainsi que des procédés de réduction de l'inflammation par administration des protéines chimériques de l'invention.

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