Nucleoside derivatives as inhibitors of viral polymerases

Details Nucleoside derivatives as inhibitors of viral polymerases Nucleoside derivatives as inhibitors of viral polymerases

C - Chemistry, Metallurgy

07

H

C07H 19/14 (2006.01) A61K 31/7064 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2735783

Compounds of structural formula (I): and pharmaceutically acceptable salts thereof; wherein R1; R2; R3;Q1and Q2 are as defined herein, processes for their preparation; pharmaceutical compositions containing them and their use in medicine, in particular the treatment or prevention of HCV infections, are disclosed.

La présente invention concerne des composés de formule structurale (I) : et des sels pharmaceutiquement acceptables de ceux-ci ; R1 ; R2 ; R3 ; Q1 et Q2 étant comme présentement définis, des procédés pour leur préparation ; des compositions pharmaceutiques contenant ceux-ci et leur utilisation en médecine, en particulier le traitement ou la prévention dinfections par le VHC.

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