Receptor infection assay

G - Physics – 01 – N

Patent

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Details

G01N 33/566 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2067216

2067216 9106677 PCTABS00005 The presente invention relates to improvements in a bioassay useful for identifying materials that function as ligands for a hormone or hormone-like receptor protein measured by means of induction of reporter DNA driven by a promoter of a hormone response element. The improvement comprises producing a cell operatively harboring DNA encoding reporter gene and receptor gene by coinfection of a mammalian cell with a viral expression vector. The expedient of this invention permits commercial realization and exploitation of the bioassay system.

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