Opioid antagonist containing composition for enhancing the...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/485 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/445 (2006.01) A61K 45/06 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2408098

0he invention generally relates to novel compositions and methods with an opioid agonist and an opioid antagonist to differentially dose a human subject so as to either enhance analgesic potency without attenuating an adverse side effect of the agonist, or alternatively maintain the analgesic potency of the agonist while attenuating an adverse side effect of the agonist. The invention additionally relates to novel opioid compositions and methods for the gender- based dosing of men and women.

L'invention concerne d'une manière générale de nouvelles compositions et méthodes faisant intervenir un agoniste opioïde et un antagoniste opioïde pour obtenir un dosage différentiel d'un sujet humain de manière à soit améliorer la puissance analgésique sans atténuer un effet secondaire indésirable de l'agoniste, soit autrement maintenir la puissance analgésique de l'agoniste tout en atténuant un effet secondaire indésirable de l'agoniste. L'invention concerne également de nouvelles compositions opioïdes et méthodes de dosage basées sur le sexe chez l'homme et la femme.

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