Hydrogenation of precursors to thiazolidinedione...

Details Hydrogenation of precursors to thiazolidinedione... Hydrogenation of precursors to thiazolidinedione...

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01)

Patent

CA 2470075

Provided is a method of hydrogenating the exocyclic double bond of a thiazolidinedione precursor in a method of making a thiazolidinedione antihyperglycemic, for example pioglitazone, including work-up steps to afford pure thiazolidinedione antihyperglycemic.

L'invention concerne une méthode d'hydrogénation de la double liaison exocyclique d'un précurseur de thiazolidinédione dans une méthode de fabrication d'une substance anti-hyperglycémiante de thiazolidinédione, par exemple le pioglitazone, comprenant des étapes permettant d'obtenir des substances antihyperglycémiantes de thiazolidinédione pures.

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