Affinity bound collagen matrices for the delivery of...

Details Affinity bound collagen matrices for the delivery of... Affinity bound collagen matrices for the delivery of...

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 17/06 (2006.01)

Patent

CA 2165727

Affinity bound collagen matrices for the delivery of biologically active agents, and methods for preparing such matrices, are disclosed. A preferred method for preparing the matrices of the invention comprises mixing a binding ligand and an active agent together, allowing the resulting binding ligand - active agent mixture to form an affinity bound complex, then combining the resulting affinity bound complex with collagen to form a matrix. Particular affinity bound matrices comprising collagen, heparin, and an active agent are also disclosed, as well as methods for using the matrices of the invention for delivery of biologically active agents.

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