A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/55 (2006.01) A61K 31/727 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2623449
Use of a direct thrombin inhibitor in the treatment of acute coronary syndrome (ACS) in a patient, comprising a therapeutically effective amount of an indirect thrombin inhibitor for an administration to the patient, and a therapeutically effective amount of the direct thrombin inhibitor for a subsequent administration to the patient; wherein the direct thrombin inhibitor is bivalirudin,wherein the indirect thrombin inhibitor is unfractionated heparin (UFH) or low molecular weight heparin (LMWH) and wherein the administration of the direct thrombin inhibitor is prior to or at the time of angiography and subsequently during a surgical procedure.
Utilisation d'un inhibiteur direct de la thrombine dans le traitement du syndrome coronarien aigu (SCA) chez un patient, comprenant l'administration au patient d'une quantité thérapeutiquement efficace d'un inhibiteur indirect de la thrombine et l'adminstration subséquente d'une quantité thérapeutiquement efficace d'un inhibiteur direct de la thrombine, où l'inhibiteur direct de la thrombine est la bivalirudine et l'inhibiteur indirect de la thrombine est une héparine non fractionnée (HNF) ou une héparine de faible poids moléculaire (HFPM) et où l'inhibiteur direct de la thrombine est administré avant ou pendant l'angiographie et, par la suite, pendant l'intervention chirurgicale.
Baldo Lance
Meanwell Clive
Plent Stephanie
Skerjanec Simona
Gowling Lafleur Henderson Llp
The Medicines Company
LandOfFree
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