Screening method for apoptosis and necrosis

Details Screening method for apoptosis and necrosis Screening method for apoptosis and necrosis

G - Physics

01

N

G01N 33/50 (2006.01) C12N 15/58 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2317463

The present invention relates to a method for the determination of non-, anti- , or pro-apoptotic and necrotic conditions of cells, newly designed vectors coding for marker proteins, cell lines transfected with such vector, and a method to assay the non-, pro- or anti-apoptotic or necrotic activity of test compounds.

La présente invention a trait à un procédé permettant de déterminer si des cellules présentent un état de non-apoptose, d'anti-apoptose ou de pro-apoptose, ou un état nécrotique; à des vecteurs récemment mis au point qui codent pour des protéines marqueurs; à des lignées cellulaires transfectées à l'aide d'un tel vecteur; et à un procédé permettant de tester une activité de non-apoptose, d'anti-apoptose ou de pro-apoptose, ou une activité nécrotique de composés d'essai.

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