Substituted benzoylguanidines, process for their...

Details Substituted benzoylguanidines, process for their... Substituted benzoylguanidines, process for their...

C - Chemistry, Metallurgy

07

C

C07C 279/22 (2006.01) A61K 31/155 (2006.01) A61K 31/165 (2006.01) A61K 31/33 (2006.01) C07D 207/337 (2006.01) C07D 213/58 (2006.01) C07D 215/14 (2006.01) C07D 217/16 (2006.01) C07D 231/12 (2006.01) C07D 263/32 (2006.01) C07D 277/30 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01)

Patent

CA 2115967

Abstract of the disclosure: Substituted benzoylguanidines, process for their preparation, their use as a pharmaceutical or diagnostic, and pharmaceutical containing them. Image (I) where R(1) to R(3) are H, Hal, (cyclo)alkyl, N3, CN or OH, alkyloxy, phenyl, phenoxy or benzoyl, and their pharmacologically acceptable salts, but with the excep- tion of the compounds benzoylguanidine, 4-chloro- benzoylguanidine, 3,4-dichlorobenzoylguanidine and 3- or 4-methylbenzoylguanidine. They are obtained by reacting a compound II Image (II) with guanidine, L being a leaving group.

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