Method of preparing thieno[3,2-c]pyridine derivatives and...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01)

Patent

CA 2559571

Ticlopidine and clopidogrel having high blood platelet aggregation inhibitory and anti-thrombotic activities are simply prepared by reacting a substituted thiophene derivative with a 2-chlorobenzylamine derivative.

Pour la fabrication de ticlopidine et de clopidogrel, qui possédant un pouvoir anti-thrombotique et inhibiteur d'agrégation plaquettaire élevé, on fait simplement réagir un dérivé de thiophène substitué et un dérivé de 2-chlorobenzylamine.

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