Essential and important genes of pseudomonas aeruginosa and...

Details Essential and important genes of pseudomonas aeruginosa and... Essential and important genes of pseudomonas aeruginosa and...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 45/00 (2006.01) A61P 31/04 (2006.01) C07K 14/21 (2006.01) C07K 16/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G06F 17/30 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2450658

The invention includes a database of candidate essential genes in Pseudomonas aeruginosa, as well as otherwise important genes that, when mutated, lead to a growth attenuated phenotype. Such genes and mutants of such genes are important for identifying antibacterial agents suitable for treating and preventing Pseudomonas aeruginosa infections. The invention includes methods for confirming the essentiality or importance of candidate genes, as well as methods for utilizing those genes to screen for new antibacterial drugs. The invention also includes the antibacterial agents identified using the disclosed methods, as well as methods of using the same for treating and preventing Pseudomonas infection.

L'invention concerne une base de données de gènes candidats essentiels dans la <i>Pseudomonas aeruginosa</i>, ainsi que d'autres gènes importants qui, une fois mutés, conduisent à un phénotype atténué de croissance. Ces gènes et les mutants de ces gènes sont importants pour une identification d'agents antibactériens appropriés au traitement et à la prévention d'infections par <i>Pseudomonas aeruginosa</i>. L'invention comprend des procédés de confirmation du caractère essentiel ou de l'importance de gènes candidats, ainsi que des procédés d'utilisation de ces gènes afin de cribler de nouveaux médicaments antibactériens. L'invention comprend également les agents antibactériens identifiés au moyen des procédés décrits, ainsi que des procédés d'utilisation de ces agents de traitement et de prévention de l'infection par <i>Pseudomonas</i>.

Affiliated with

Also associated with

Rating

Essential and important genes of pseudomonas aeruginosa and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Essential and important genes of pseudomonas aeruginosa and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Essential and important genes of pseudomonas aeruginosa and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1725623