Characterization of a calcium channel family

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2360396

Nucleic acids encoding SOC/CRAC calcium channel polypeptides, including fragments and biologically functional variants thereof and encoded polypeptides are provided. The nucleic acids and polypeptides disclosed herein are useful as therapeutic and diagnostic agents. Agents that selectively bind to the foregoing polypeptides and genes also are provided.

L'invention porte sur des acides nucléiques codant des polypeptides des canaux calciques SOC/CRAC, notamment des fragments et des variants biologiquement fonctionnels desdits fragments, et des polypeptides codés. Les acides nucléiques et les polypeptides de l'invention sont utiles comme agents thérapeutiques ou diagnostiques. L'invention porte en outre sur des agents qui se lient auxdits polypeptides et gènes.

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