C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 9/16 (2006.01) A61K 9/51 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 38/28 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C12N 15/10 (2006.01)
Patent
CA 2290071
Targeting agents that are capable of permitting or facilitating transport of an active agent through a human or animal gastro-intestinal tissue. These targeting agents are peptides or their derivatives (e.g., fragments) and peptidomimetics thereof, and the nucleotide sequences coding for the peptides and derivatives. The targeting agents have use in facilitating transport of active agents from the lumenal side of the GIT into the systemic blood system, and/or in targeting active agents to the GIT. Therapeutic methods of administration, pharmaceutical compositions and formulations based on the targeting agent peptides are also provided. Preferably, the active agent is a drug or drug-containing nano- or microparticle.
L'invention concerne des agents de ciblage permettant ou facilitant le transport d'un agent actif dans des tissus gastro-intestinaux humains ou animaux. Ces agents de ciblage sont des peptides, ou leurs dérivés (par exemple des fragments) et leur peptidomimétique, ainsi que les séquences codant ces peptides et leurs dérivés. L'utilisation de ces agents de ciblage facilite le transport d'agents actifs de la lumière du tractus gastro-intestinal à l'ensemble du système cardio-vasculaire, et/ou cible lesdits agents actifs vers ledit tractus gastro-intestinal. L'invention concerne également des procédés d'administration thérapeutiques ainsi que des compositions et des formulations pharmaceutiques à base des peptides agents de ciblage. L'agent actif est de préférence un médicament, ou une microparticule ou une nanoparticule renfermant un médicament.
Alvarez Vernon Leon
O'mahony Daniel Joseph
Seveso Michela
Cytogen Corporation
Elan Corporation Plc
Kirby Eades Gale Baker
LandOfFree
Peptides which enhance transport of an active agent across... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptides which enhance transport of an active agent across..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides which enhance transport of an active agent across... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1725912