Optimization of colicin production

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/21 (2006.01) A23B 4/20 (2006.01) C12N 15/31 (2006.01) C12N 15/74 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2686554

High colicin producing bacteria strains are produced by introducing into a host cell multiple copies of a plasmid containing a colicin gene. A suitable host cell is a bacterium strain, Escherichia coli K-12 and examples of plasmids are pColE1-K53 or pColN-284.

Des souches de bactérie produisant un taux élevé de colicine sont obtenues par l'introduction dans une cellule hôte de multiples copies d'un plasmide contenant un gène de colicine. Une cellule hôte appropriée est une souche de bactéries, Escherichia coli K-12 et des exemples de plasmide sont pColE1-K53 ou pColN-284.

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