C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2536335
The subject invention relates to a multiple-allelic RT-real-time polymerase chain reaction (PCR) assay for coronaviruses including the SARS virus. Multiple target sequences within the SARS-CoV, S, E, M and N genes are identified. The use of the four different targets enhances the likelihood that the fundamental genetic drift of the virus will not lead to a false negative result. Multiplex assays format for the assay are envisioned. Thus, the present invention allows for early diagnosis of a SARS infection. The assay would be useful in the context of monitoring treatment regimens, screening potential anti SARS agents, and similar applications requiring qualitative and quantitative determinations.
L'invention concerne un essai PCR multi-allélique en temps réel pour coronavirus, y compris le virus SARS. On identifie des séquences cibles multiples dans les gènes suivants: SARS-CoV, S, E, M et N. L'utilisation de quatre cibles différentes améliore la probabilité que la dérive génétique fondamentale du virus ne donne pas de résultat négatif erroné. ON décrit un format d'essai multiplex. Dès lors, il est possible d'effectuer un diagnostic précoce de l'infection par le SARS. Ce type d'essai est utile dans le cadre du contrôle de régime de traitement, de la recherche d'agents potentiels anti-SARS et autres applications identiques nécessitant des déterminations qualitatives et quantitatives.
Birch Biomedical Research Llc
Smart & Biggar
LandOfFree
Multi-allelic molecular detection of sars-associated... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-allelic molecular detection of sars-associated..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-allelic molecular detection of sars-associated... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1727167