Method for producing an implantable bone composition

Details Method for producing an implantable bone composition Method for producing an implantable bone composition

A - Human Necessities

61

L

A61L 27/22 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2716745

Disclosed are methods for producing implantable bone compositions suitable for at- taching stem cells thereto, characterized in that bone particles are contacted with an albumin comprising solution. Said bone particles can be mineralized and/or lyophilized bone particles of animal or human origin. Preferably the non-immunogenic albumin comprising solution is lyophilized onto said bone particles. The invention further concerns bone compositions suit- able for use in graft implantation obtainable by said methods.

L'invention concerne des méthodes de production de compositions osseuses implantables adaptées pour recevoir des cellules souches, se caractérisant en ce que les particules osseuses viennent en contact avec une solution contenant de l'albumine. Lesdites particules osseuses peuvent être des particules osseuses minéralisées et/ou lyophilisées d'origine animale ou humaine. La solution contenant de l'albumine non immunogène est, de préférence, lyophilisée sur lesdites particules osseuses. L'invention concerne également des compositions osseuses adaptées pour être utilisées dans l'implantation de greffes, pouvant être obtenues par lesdites méthodes.

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