Use of (r)-ibuprofen methanesulfonamide and salts thereof in...

A - Human Necessities – 61 – K

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A61K 31/216 (2006.01) A61K 31/192 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2432432

The use of (R).-ibuprofen methanesulfonamide is described for the preparation of medicaments for the treatment and prevention of functional injury resulting from rejection reactions of transplanted organs. In particular, the use of non- toxic salts of (R)-ibuprofen methanesulfonamide, such as the (L)-lysine salt, is described for the prevention and the treatment of rejection reactions of transplanted kidneys.

La présente invention concerne l'utilisation de (R)-ibuprofène méthane sulfonamide pour préparer des médicaments permettant le traitement et la prévention des lésions fonctionnelles résultant de réactions de rejet à la suite de transplantations d'organes. En particulier, l'invention a pour objet l'utilisation de sels non toxiques de (R)-ibuprofène méthane sulfonamide, tels que le sel de (L)-lysine, pour la prévention et le traitement des réactions de rejet à la suite de la transplantation de reins.

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