Compositions and methods for preventing influenza infection...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/86 (2006.01) A61K 39/145 (2006.01)

Patent

CA 2696963

The present invention is directed to the use of recombinant, chimeric mononegavirale vectors comprising a foreign gene. More particularly, the present invention is directed to the use of such vectors for treating respiratory diseases in canines, felines or equines. An embodiment of the present invention is the use of a recombinant Newcastle disease virus vector comprising a hemagglutinin from an H3N8 influenza in the protection or treatment of canines, equines or felines against influenza.

La présente invention concerne l'utilisation de vecteurs chimériques recombinants des Mononegavirales comprenant un gène étranger. L'invention concerne plus particulièrement l'utilisation de tels vecteurs pour traiter des maladies respiratoires chez des canidés, des félins ou des équidés. Un mode de réalisation de la présente invention est l'utilisation d'un vecteur recombinant du virus de la maladie de Newcastle comprenant une hémagglutinine provenant d'un virus grippal H3N8 pour la protection ou le traitement de canidés, de félins ou d'équidés contre la grippe.

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