C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2392946
The invention provides isolated nucleic acid molecules, designated ABCB9 transporter nucleic acid molecules, which encode novel ABC transporter family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing ABCB9 transporter nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an ABCB9 transporter gene has been introduced or disrupted. The invention still further provides isolated ABCB9 transporter proteins, fusion proteins, antigenic peptides, anti-ABCB9 transporter antibodies, and screening assays for ABCB9 transporter modulators. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
L'invention concerne des molécules d'acide nucléique isolées, désignées molécules d'acide nucléique de transporteur ABCB9, codant de nouveaux membres de la famille du transporteur ABC9. Elle concerne également des molécules d'acide nucléique antisens, des vecteurs d'expression recombinants contenant ces molécules d'acide nucléique du transporteur ABC9, des cellules hôtes dans lesquelles on a introduit ces vecteurs d'expression, ainsi que des animaux transgéniques non humains dans lesquels on a introduit ou dissocié un gène du transporteur ABCB9. Elle concerne également des protéines isolées du transporteur ABCB9, des protéines de fusion, des peptides antigéniques, des anticorps antitransporteur ABCB9 et des méthodes de criblage concernant des modulateurs du transporteur ABCB9. Elle concerne encore des procédés diagnostiques et thérapeutiques mettant en application ces compositions.
Active Pass Pharmaceuticals Inc.
Borden Ladner Gervais Llp
LandOfFree
Novel abcb9 transporter and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel abcb9 transporter and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel abcb9 transporter and uses thereof will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1731961