C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/01 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 35/76 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/42 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2201587
The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immumostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provided using the composition.
La présente invention concerne une composition d'un virus de recombinaison qui comprend dans son génome ou dans une partie de celui-ci un gène codant pour un antigène d'un agent provoquant une maladie et d'un virus de recombinaison qui comprend dans son génome ou dans une partie de celui-ci un gène codant pour une ou des molécules immunostimulatrices, pour stimuler la réponse immunitaire vis-à-vis de l'agent provoquant une maladie. On décrit également des méthodes de traitement de maladies telles que le cancer ou de maladies causées par des micro-organismes pathogènes, en utilisant la composition en question.
Kantor Judith
Schlom Jeffrey
Department Of Health And Human Services The Government Of The United States Of America Represented By Th
Smart & Biggar
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