Method of identifying compounds that modulate interaction of...

Details Method of identifying compounds that modulate interaction of... Method of identifying compounds that modulate interaction of...

Category

C - Chemistry, Metallurgy

Subcategory

12

Subsubcategory

N

IPC codes

C12N 15/10 (2006.01)

Type

Patent

Patent number

CA 2607963

Description

Methods for determining if test compounds are able to modulate the interaction between adrogen receptor and beta-catenin are disclosed. Methods for the determining whether a test compound selectively modulates an adrogen receptor signaling pathway over a beta-catenin-Wnt signaling pathway or a beta-catenin- Wnt signaling pathway over an androgen receptor signaling pathway are also disclosed.

La présente invention a trait à des procédés pour déterminer si des composés d'essai sont capables de moduler l'interaction entre le récepteur androgène et la bêta-caténine. L'invention a également trait à des procédés pour déterminer si un composé d'essai réalise la modulation sélective d'une voie signalisation du récepteur d'androgène sur une voie de signalisation Wnt/bêta-caténine ou une voie de signalisation Wnt/bêta-caténine sur une voie de signalisation du récepteur androgène.

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