C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) C07D 215/22 (2006.01) C07D 239/86 (2006.01) C07D 239/91 (2006.01) C07D 239/93 (2006.01) C07D 307/79 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01)
Patent
CA 2507381
The present invention relates to methods of producing quinazoline compounds (I) and derivatives thereof which are useful as Rho-kinase Inhibitors or intermediates thereof (3). Rho-kinase inhibitors are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
La présente invention a trait à des procédés de production de composés quinazoline de structure (I) et de leurs dérivés utiles en tant qu'inhibiteurs de Rho-kinase ou leurs intermédiaires de structure (3). Les inhibiteurs de Rho-kinase sont utiles pour l'inhibition de croissance tumorale, le traitement de la dysérection, et le traitement d'autres conditions provoquées par la Rho-kinase, par exemple, la cardiopathie coronaire.
Asgari Davoud
Bankston Donald
Boyer Stephen
Hart Barry
Khire Uday
Bayer Healthcare Llc
Bayer Pharmaceuticals Corporation
Goodwin Mckay
LandOfFree
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