Use of bicyclo compounds for treating alzheimer's disease

Details Use of bicyclo compounds for treating alzheimer's disease Use of bicyclo compounds for treating alzheimer's disease

A - Human Necessities

61

K

A61K 31/439 (2006.01) A61K 31/35 (2006.01) A61K 31/353 (2006.01) A61K 31/382 (2006.01) A61K 31/46 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2451664

Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of compounds of formula (I) wherein X, Y, Z, R1, R2, and R3 are defined herein.

L'invention concerne des procédés de traitement de la maladie d'Alzheimer, et d'autres maladie, et/ou d'inhibition de l'enzyme beta-sécrétase, et/ou d'inhibition du dépôt de peptide beta A chez un mammifère, au moyen de composés représentés par la formule (I) où X, Y, Z, R1, R2, et R3 ont la signification indiquée dans la description.

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