Treatment of skin damage using polyenylphosphatidylcholine

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/685 (2006.01) A61K 8/55 (2006.01) A61Q 19/00 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2400740

Polyenylphosphatidylcholine is topically applied to treat skin damage, such as contact dermatitis (particularly diaper area dermatitis), atopic dermatitis, xerosis, eczema (including severe hand and foot eczema), rosacea, seborrhea, psoriasis, thermal and radiation burns, other types of skin inflammation, and aging. Typical compositions contain from about 0.25 % to about 10 % of a polyenylphosphatidylcholine preparation obtained form natural sources such as soybean oil which contains at least about 25 % by weight, preferably about 40 % or more, dilinoeoylphosphatidylcholine.

L'invention concerne l'application par voie topique de polyénylphosphatidylcholine pour traiter les lésions cutanées telles que la dermatite de contact (en particulier l'érythème fessier), la dermatite atopique, la xérose, l'eczéma (y compris l'eczéma sévère des mains et des pieds), l'acné rosacée, la séborrhée, le psoriasis, les brûlures thermiques et les brûlures par irradiation, d'autres types d'inflammation cutanée, et le vieillissement. Les compositions typiques contiennent d'environ 0,25 % à environ 10 % d'une préparation de polyénylphosphatidylcholine obtenue de sources naturelles telles que l'huile de soja qui contient au moins environ 25 % en poids, et de préférence environ 40 % ou plus, de dilinoéoylphosphatidylcholine.

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