Anhydrovinblastine for the treatment of cancer

Details Anhydrovinblastine for the treatment of cancer Anhydrovinblastine for the treatment of cancer

A - Human Necessities

61

K

A61K 31/475 (2006.01)

Patent

CA 2266957

The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an anti-neoplastic agent in the therapeutic treatment of cancer.

L'invention concerne en particulier l'utilisation d'un dérivé de la vinblastine, la 3',4'-anhydrovinblastine (AHVB), qui diffère de la vinblastine par le fait qu'elle possède une double liaison en position 3',4' du noyau caranthine à la place du groupe hydroxyle présent dans la structure apparentée, comme agent antinéoplasique dans le traitement du cancer.

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