Novel antibacterial compounds

Details Novel antibacterial compounds Novel antibacterial compounds

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 39/44 (2006.01) A61K 47/48 (2006.01) A61K 51/00 (2006.01) C07C 233/36 (2006.01) C07C 233/78 (2006.01) C07C 237/24 (2006.01) C07C 271/20 (2006.01) C07C 335/08 (2006.01) C07C 335/32 (2006.01) C07D 207/333 (2006.01) C07D 211/58 (2006.01) C07D 215/56 (2006.01) C07D 233/90 (2006.01) C07D 235/30 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/04 (2006.01) C07D 413/14 (2006.01) C07D 471/04

Patent

CA 2321162

Novel multibinding compounds are disclosed. The compounds of the invention comprise from 2-10 ligands covalently connected, each of said ligands being capable of inhibiting bacterial Type II DNA topoisomerase, thereby modulating the biological processes/functions thereof.

La présente invention concerne des composés à liaisons multiples. Ces composés comportent de 2 à 10 ligands reliés par covalence. Chacun des ligands considérés est capable d'inhiber la topoisomérase de l'ADN bactérienne de type II. Cela permet à ces ligands de moduler les processus et les fonctions biologiques de cette topoisomérase.

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