C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) C07D 207/00 (2006.01) C07D 209/00 (2006.01) C07D 239/00 (2006.01) C07D 333/00 (2006.01) C07D 405/14 (2006.01) C07D 407/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2394852
Disclosed are substituted pyrroles having formula (I), wherein R1, R2, R1' and R2' are as defined in the claims and in the description. These compounds and their pharmaceutically acceptable salts are useful in the treatment and/or control of cell proliferative disorders, in particular cancer. Also disclosed are pharmaceutical compositions containing the foregoing compounds.
L'invention concerne des pyrroles substitués représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?1'¿ et R?2'¿ sont tels que définis dans les revendications et dans la description. Ces composés et leurs sels acceptables d'un point de vue pharmaceutique sont utilisés dans le traitement et/ou le contrôle de troubles associés à la prolifération des cellules, en particulier le cancer. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés.
Fotouhi Nader
John Lovey Allen
Kong Norman
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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