Novel amide derivatives as inhibitors of matrix...

Details Novel amide derivatives as inhibitors of matrix... Novel amide derivatives as inhibitors of matrix...

C - Chemistry, Metallurgy

07

C

C07C 259/06 (2006.01) A61K 31/16 (2006.01) A61P 43/00 (2006.01) C07C 317/50 (2006.01) C07C 323/59 (2006.01) C07D 207/16 (2006.01) C07D 211/60 (2006.01) C07D 213/30 (2006.01) C07D 215/14 (2006.01) C07D 249/18 (2006.01) C07D 261/08 (2006.01) C07D 295/185 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2366264

The present application describes novel amides and derivatives thereof of formula (I) or pharmaceutically acceptable salt forms thereof, wherein these compounds are useful as inhibitors of matrix metalloproteinases, TNF-.alpha., and aggrecanase.

La présente invention concerne de nouveaux amides et des dérivés de ceux-ci, de formule (I), ou des formes salines pharmaceutiquement acceptables de ceux-ci, ces composés pouvant être utilisés comme inhibiteurs de métalloprotéases matricielles, de TNF-alpha, et de l'aggrécanase.

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