Self-emulsifying compositions for drugs poorly soluble in water

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A01N 37/10 (2006.01) A01N 43/02 (2006.01) A61K 9/107 (2006.01) A61K 9/48 (2006.01) A61K 31/192 (2006.01) A61K 31/337 (2006.01) A61K 38/13 (2006.01)

Patent

CA 2354233

The present invention is directed to a pharmaceutical composition comprising a pharmaceutically effective amount of a lipophilic drug, in association with a pharmaceutical carrier, said carrier comprising a lipophilic drug solubilizing effective amount of a propylene glycol monoester of C6-C18 fatty acid having at least 60 % by weight monoester based on the total weight of the propylene glycol ester and a non-ionic surfactant.

La présente invention concerne une composition pharmaceutique comprenant une quantité pharmacologiquement efficace d'un médicament lipophile, associé à un excipient pharmaceutique. Ledit excipient comprend une quantité efficace pour la solubilisation du médicament lipophile, d'un monoester du propyléne glycol d'acides gras C¿6-?C¿18? ayant au moins 60 % en poids de monoester sur la base du poids total de l'ester du propylène glycol, et un agent de surface non ionique.

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